[mod_python] URLs

I want to configure mod_python to not process the URL and just handle 
the request at the root level.

In other words, a request to:

http://example.com/this/path/is/not/to/be/processed

Needs to be handled by index.py at the root level. And index.py 
internally process the rest of the URI 
'this/path/is/not/to/be/processed'.

So, my question is how can I configure mod_python for accomplishing 
this.

Regards,
/amn