A handler is a function that processes a particular phase of a request. Apache processes requests in phases - read the request, process headers, provide content, etc. For every phase, it will call handlers, provided by either the Apache core or one of its modules, such as mod_python which passes control to functions provided by the user and written in Python. A handler written in Python is not any different from a handler written in C, and follows these rules:
    A handler function will always
be passed a reference to a request object. (Throughout this manual,
the request object is often referred to by the req variable.)
Every handler can return:
    HTTP_CONTINUE                     = 100
    HTTP_SWITCHING_PROTOCOLS          = 101
    HTTP_PROCESSING                   = 102
    HTTP_OK                           = 200
    HTTP_CREATED                      = 201
    HTTP_ACCEPTED                     = 202
    HTTP_NON_AUTHORITATIVE            = 203
    HTTP_NO_CONTENT                   = 204
    HTTP_RESET_CONTENT                = 205
    HTTP_PARTIAL_CONTENT              = 206
    HTTP_MULTI_STATUS                 = 207
    HTTP_MULTIPLE_CHOICES             = 300
    HTTP_MOVED_PERMANENTLY            = 301
    HTTP_MOVED_TEMPORARILY            = 302
    HTTP_SEE_OTHER                    = 303
    HTTP_NOT_MODIFIED                 = 304
    HTTP_USE_PROXY                    = 305
    HTTP_TEMPORARY_REDIRECT           = 307
    HTTP_BAD_REQUEST                  = 400
    HTTP_UNAUTHORIZED                 = 401
    HTTP_PAYMENT_REQUIRED             = 402
    HTTP_FORBIDDEN                    = 403
    HTTP_NOT_FOUND                    = 404
    HTTP_METHOD_NOT_ALLOWED           = 405
    HTTP_NOT_ACCEPTABLE               = 406
    HTTP_PROXY_AUTHENTICATION_REQUIRED= 407
    HTTP_REQUEST_TIME_OUT             = 408
    HTTP_CONFLICT                     = 409
    HTTP_GONE                         = 410
    HTTP_LENGTH_REQUIRED              = 411
    HTTP_PRECONDITION_FAILED          = 412
    HTTP_REQUEST_ENTITY_TOO_LARGE     = 413
    HTTP_REQUEST_URI_TOO_LARGE        = 414
    HTTP_UNSUPPORTED_MEDIA_TYPE       = 415
    HTTP_RANGE_NOT_SATISFIABLE        = 416
    HTTP_EXPECTATION_FAILED           = 417
    HTTP_UNPROCESSABLE_ENTITY         = 422
    HTTP_LOCKED                       = 423
    HTTP_FAILED_DEPENDENCY            = 424
    HTTP_INTERNAL_SERVER_ERROR        = 500
    HTTP_NOT_IMPLEMENTED              = 501
    HTTP_BAD_GATEWAY                  = 502
    HTTP_SERVICE_UNAVAILABLE          = 503
    HTTP_GATEWAY_TIME_OUT             = 504
    HTTP_VERSION_NOT_SUPPORTED        = 505
    HTTP_VARIANT_ALSO_VARIES          = 506
    HTTP_INSUFFICIENT_STORAGE         = 507
    HTTP_NOT_EXTENDED                 = 510
As an alternative to returning an HTTP error code, handlers can signal an error by raising the apache.SERVER_RETURN exception, and providing an HTTP error code as the exception value, e.g.
raise apache.SERVER_RETURN, apache.HTTP_FORBIDDEN
Handlers can send content to the client using the req.write() method.
Client data, such as POST requests, can be read by using the req.read() function.
Python*Handler 
  directive in effect is prepended to the sys.path. If the
  directive was specified in a server config file outside any
  <Directory>, then the directory is unknown and not prepended.
An example of a minimalistic handler might be:
from mod_python import apache
def requesthandler(req):
    req.content_type = "text/plain"
    req.write("Hello World!")
    return apache.OK